Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/304421640?client_source=feed&format=rss
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Wednesday, May 8, 2013
Social Media: A Crucial Component for Success | Other Side Group
<img class=?alignleft wp-image-2219? style=?margin: 10px;? src=?http://www.b2bvoices.com/wp-content/uploads/2013/05/Steve-Nicholls-Headshot?150?150.png? alt=?Steve Nicholls Headshot? width=?150? height=?150? />This is a guest post by?Steve Nicholls, author of the best-selling?Social Media in Business
Thinking of a business strategy without social media has become antiquated, unless you travel at least 20 years back in time. Today, a business is no longer sustainable without an effective social media agenda. Even giant organizations like Starbucks, Groupon, Reuters or British Airways have all started to incorporate social media; this is because businesses simply cannot do without it any longer.
Social media can be defined as the experience of sharing content online, whether music, videos, pictures, comments, reviews and news among other forms. Once, the ?brochure site? ruled over the Internet, static and imposing, allowing Internet users to simply view content passively. Today, anyone, anywhere and at anytime can generate and share content on the Internet: this is social media.
Social media is materialized through its many applications. The differences between each one are very wide, which means a range of activities can be done through social media. To give just a very few examples, Twitter can be used to send short messages instantly to a group of followers, Yahoo! Answers gives the chance to ask questions to the entire web community and receive a plethora of answers, Wikinews allows people to work jointly in order to write objective news articles and GoToWebinar is a conferencing tool that makes long-distance training possible.
Furthermore, each application is a world of small applications. LinkedIn, for instance, is very useful for the creation of a professional hub of current and past co-workers, who become <em>connections.</em> These in turn can link you to their own connections so that you become at the center of a web of professional connections ? generating a lot of opportunities for network-building. Next to that, LinkedIn Answers allows users to ask business-related questions to their network as well as the bigger LinkedIn hub. Also, LinkedIn?s reference check helps users search for references on a potential employee or employer. These options are only a very few examples of what LinkedIn offers but shows how social media is extensive in both breadth and depth.
In a business context, interchange via all these applications can take place between the company and its customers, between customers themselves but also within a company and finally, within a business-to-business environment as well. Steve Nicholls, author of the book Social Media in Business, explores these avenues in depth. He explains that ?this sharing allowed by social media translates into invaluable opportunities for businesses,? which he divides into five main categories.
First and foremost, social media gives access to the largest marketplace on the planet. In a matter of a few seconds, companies can transcend traditional boundaries to reach more people or create a presence beyond geographical limits. This gives rise to the second opportunity: communication. Social media improves communication between any two or more parts of a business: between employees, between staff and customers or between upper and lower staff. Blogs, for example, are a very good way for a company to communicate with its customers and having a Facebook Page can be useful to create an internal online community amongst employees, especially the bigger the organization is.
Third, social media allows managers to tap into communities where prospects ? such as customers, freelancers, business connections, etc. ? can be found or created. Every time this happens, it is not one individual that is found but an entire pool of prospects. For example, a Facebook Fan Page is great to nurture a community of customers and keep them updated with product news while Elance is a community of freelancers with all sorts of skills where the ?right person for the job? can be found.
Fourth, social media allows businesses to get information from collective intelligence, i.e. the ?global brain? of the web community, as Tim O?Reilly, founder of O?Reilly Media, defines it. Exploiting this facet of social media means that companies can obtain competitor intelligence, customer insights or find cost-effective business solutions. For example, through Brainrack, companies can crowdsource business-related issues to students and get a diversity of solutions and the student with the best solution wins a prize. Rating systems are another way to use collective intelligence to find out how much consumers like a certain product for instance.
Finally, social media allows collaboration, i.e. co-working on a certain project, or participating in its development. A very simple application is Skype, through which colleagues living in different countries can form an online conferencing room. DropBox is an excellent tool to create files which can be accessed by colleagues online, from anywhere in the world.
By adopting a good social media strategy, a company can thus leverage its competitive advantage substantially. Nicholls however stresses the use of social media within a company must be clearly fitted to its general business goals to avoid going enthusiastically in the wrong direction. Nicholls also warns that social media does have a ?dark side? and that managers should be aware of its pitfalls, but that these, if properly prepared for, are just a small obstacle in comparison to social media?s great potential. Adopting a successful strategy is one that will take advantage of social media in the context of a company?s business goals, while at the same time mitigating its risks.
<strong>Steve Nicholls Bio</strong>
<img class=?alignright wp-image-2221? style=?margin: 10px;? src=?http://www.b2bvoices.com/wp-content/uploads/2013/05/Book-Cover-Image?150?150.jpg? alt=?Book Cover Image? width=?150? height=?150? />Steve Nicholls is the author of the best-selling Social Media in Business,?international speaker, and social media strategist who helps business executives implement a winning social media strategy into their organization. After beginning his career as a project manager in skyscraper construction, Steve earned his MBA at Henley Business School in 1992 and his Masters of Science in Organizational Development from the University of Portsmouth in 2008.? His background as a project manager, combined with his extensive experience in the business and technology industries, has given him the unique ability to help companies lay their own blueprint for social media success. www.socialmediainbusiness.com
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MicroRNA cooperation mutes breast cancer oncogenes
May 7, 2013 ? A University of Colorado Cancer Center study recently published in the journal Cell Death & Disease shows that turning up a few microRNAs a little may offer as much anti-breast-cancer activity as turning up one microRNA a lot -- and without the unwanted side effects.
It's a bit like the classic thought experiment known as the "tumor problem" formulated by Karl Dunker in 1945 and used frequently in the problem-solving literature: Imagine a person suffers from a malignant tumor in the center of her body. Radiation strong enough to kill the tumor kills any healthy tissue through which it passes. Without operating or killing healthy tissue, how can a doctor use radiation to kill the tumor?
The answer is to target the tumor from many angles -- many weak rays of radiation pass harmlessly through healthy tissue, but their combined power at the point of the tumor is enough to kill it.
In the present study, CU Cancer Center investigators used "weak" induction of multiple microRNAs that combined from many angles to regulate the known breast cancer oncogenes erbB2/erbB3 (the "tumor") without regulating non-target genes (the "healthy tissue").
"Imagine you have a microRNA that regulates genes A and B. Then you have another microRNA that regulates genes B and C. You amplify each microRNA to a degree that doesn't effect gene A or C, but their combined effect regulates gene B," says Bolin Liu, MD, assistant professor in the Department of Pathology at the University of Colorado School of Medicine.
microRNA is an attractive target in cancer therapy -- more microRNA can lead to less gene expression, turning down or off the oncogenes that cause cancer. However, to get the desired effect on gene expression frequently requires enhancing microRNA expression 100- or 1,000-fold (or more). And the induced microRNA likely has other genetic targets -- it will turn down other genes as well as the oncogene, sometimes with unfortunate consequences.
"The current study showed that two microRNAs enhanced only 3-to-6 times their natural expression could cooperate to regulate an oncogene that had previously only been affected by a microRNA enhanced by many, many times this amount," Liu says.
Specifically, the group's work shows that no one alone, but any two of the three microRNAs that regulate erbB2/erbB3 expression can affect the levels of proteins produced by the genes. These are miR-125a, miR-15b, and miR-205, which act in concert to regulate the expression of erbB2/erbB3, which are cancer-causing products of the oncogenes.
But in general, the group's novel technique could have implications far past erbB2/erbB3, allowing researchers and eventually doctors to mute the genes they want to mute without also dampening the expression of genes regulated by only one or only the other microRNA partner.
Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.
Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/YZOg3TD17iw/130507134649.htm
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Tuesday, May 7, 2013
'Fruitvale Station' Poster Debut: Sundance Favorite Gets New Look (PHOTO)
Get used to hearing about "Fruitvale Station." The new drama from first-time writer-director Ryan Coogler was acquired by The Weinstein Company at the Sundance Film Festival in January after a wave of buzz positioned "Fruitvale Station" (then titled "Fruitvale") as the next big thing and a serious awards contender. That hum proved somewhat prescient: Following the acquisition, "Fruitvale Station" went on to win both the audience award and grand jury prize from the Sundance Film Festival.
Starring Michael B. Jordan and Octavia Spencer, "Fruitvale Station" tells the true story of Oscar Grant (Jordan), who was shot and killed at age 22 by a BART police officer at the Fruitvale station in Oakland, Calif. on New Year's Day in 2009. Grant's death was caught on video thanks to cell phone cameras focused on his arrest, and the footage sparked outrage around the country. "Fruitvale Station" deals with the last day of Grant's life.
"The pressure of playing a real person is 100-times greater [than normal]," Jordan, best known for his work on "Friday Night Lights" and in "Chronicle," told HuffPost at Sundance. "One day, his daughter is going to watch this movie. That was something I constantly thought about. His mom is going to watch this movie. I didn?t want to let anybody down. At the premiere in Sundance on Saturday, his aunt stood up and said, 'You know, Mike, there were certain times in the movie where I couldn't tell Oscar from you,' and that's the biggest compliment I ever could have gotten."
The Weinstein Company is set to release "Fruitvale Station" on July 26. Below, find the film's new theatrical poster, debuting exclusively here at HuffPost Entertainment and on our sister site, Moviefone.
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Source: http://www.huffingtonpost.com/2013/05/07/fruitvale-station-poster_n_3229465.html
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How to Open 24 Beer Bottles at Once
Got a lot of friends visiting? Man, it's going to be boring to open each and every bottle of beer separately?so what you need is an opener like this, that can ready 24 beers for drinking in a glorious, single movement.
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Source: http://feeds.gawker.com/~r/gizmodo/full/~3/wwFsar1BuY0/how-to-open-24-beer-bottles-at-once-493106776
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'Iron Man 3' Made Enough Money To Rebuild Tony Stark's House
After spending a week cleaning up at the foreign box office, Iron Man turned his sights to his home country, the good old U.S. of A., and once here, the latest Marvel movie continued to break records. "Iron Man 3" kicked off its domestic release to the tune of $175 million, good enough for the [...]
Source: http://moviesblog.mtv.com/2013/05/06/iron-man-3-box-office/
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Cause of California wildfire appears accidental
CAMARILLO, Calif. (AP) ? Investigators say the cause of a huge wildfire burning through Southern California's coastal mountains appears to be accidental.
Fire spokesman Tom Piranio says Saturday that the 44-square-mile fire at the western end of the Santa Monica Mountains was started by an undetermined ignition of grass and debris on the side of U.S. 101. He says it's possible a piece of metal fell into the tinder-dry bush early Thursday, sparking an uphill fire that was quickly stoked by hot, windy weather.
The fire threatened thousands of homes as it marched to the coast, but only caused damage to just 15 homes.
Cool, moist air that returned to the region late Friday helped firefighters gain control of the blaze. It is 75 percent contained.
Source: http://news.yahoo.com/cause-california-wildfire-appears-accidental-020559110.html
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